TITLE: Fundamental Physics from the Sky ABSTRACT: Can we learn about New Physics with astronomical and astro-particle data? Understanding how this is possible is key to unraveling one of the most pressing mysteries at the interface of cosmology and particle physics: the fundamental nature of dark matter. Rapid progress may be within grasp in the context of an approach which combines information from high-energy particle physics with cosmic-ray and traditional astronomical data. I discuss recent puzzling data on cosmic-ray electrons and positrons and their interpretation. I show how the Fermi Space Telescope will soon shed light on those data as well as potentially on several dark matter particle properties. I then introduce a novel approach to particle dark matter searches based on the complementarity of astronomical observations across the electromagnetic spectrum, from radio to X-ray and to gamma-ray frequencies.